Renata Zarazúa upsets Madison Keys in 2025 US Open 1st round

NEW YORK -- Australian Open champion Madison Keys was undone by 89 unforced errors and was upset in the first round of the US Open 6-7 (10), 7-6 (3), 7-5 by Mexico's Renata Zarazúa on Monday.

The sixth-seeded Keys, who was the runner-up at Flushing Meadows in 2017, made so many mistakes, including 14 double faults, that Zarazúa needed to produce just eight winners to earn the biggest victory of her career.

The 82nd-ranked Zarazúa had lost in either the first or second round in all eight of her previous Grand Slam appearances. She became the first Mexican player to knock off a top-10 seed at a major since Angélica Gavaldón, who defeated No. 3 seed Jana Novotná in the round of 16 at the 1995 Australian Open.

Before Keys, the last American woman seeded in the top 10 to lose in the first round at Flushing Meadows was No. 8 Chanda Rubin in 2003, to María Vento-Kabchi. It's the only other instance of it happening at the New York tournament in the past 30 years.

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Keys earned her first major championship at Melbourne Park in January, defeating No. 1 Aryna Sabalenka in the final. In addition to her run to the final in New York eight years ago before losing to good friend Sloane Stephens, Keys also was a semifinalist at the US Open in 2018 and 2023.

But with her left thigh heavily taped Monday, the big-hitting Keys struggled for stretches in Arthur Ashe Stadium against the 5-foot-3 Zarazúa, who came into the day with a 0-6 record against opponents ranked in the top 10.

"I'm a little bit small in height, so coming in here, it was like: 'Oh, my god. This is huge," Zarazúa said about the largest stadium in Grand Slam tennis, which holds nearly 24,000 spectators.

"When I retire, I'm going to be really happy about it," Zarazúa said, "so I was like, 'Just enjoy it.'"

This one certainly was memorable, in part because it did not come easily -- even though Keys kept having problems and Zarazúa kept moving ahead across the 3 hours, 10 minutes of action.

The trouble for Zarazúa was that she had a hard time closing the deal.

She went up 4-2 in the first set, then was a point from owning it five times, but couldn't convert any of those opportunities. Eventually, Keys converted her third set point.

In the second set, Zarazúa fell behind 3-0, then took five games in a row to lead 5-3. She trailed 6-5 after another run by Keys, but this time came through in the tiebreaker to force a third set.

Zarazúa led in the decider and served for the win at 5-3, but Keys broke there and then held for 5-all.

At the end, though, Zarazúa took the last two games.

While Keys was one of 25 American players in the women's singles draw at their home Grand Slam tournament, Zarazúa is Mexico's lone entrant in the bracket.

"It's a country that we don't have many tennis players, as you can see," Zarazúa said. "We just try to give our best. But definitely, I could hear some Mexicans cheering, so that was very nice."

In other women's singles results Monday, two-time major champion Barbora Krejcikova took down 18-year-old Canadian Victoria Mboko, an emerging star who was making her US Open main draw debut fresh off her title run at Montreal, where she defeated four former major champions en route to her first WTA title.

Krejcikova is unseeded at Flushing Meadows, the first time she has been unseeded at a Slam since the 2021 French Open, where she went on to win her first major singles title.

Also Monday, Belgium's Elise Mertens, the No. 19 seed, beat American Alyssa Ahn 6-1, 6-0, and No. 17 seed Liudmila Samsonova got past Yuan Yue 2-6, 6-4, 6-4.

Two-time Wimbledon champion Petra Kvitova was beaten 6-1, 6-0 by France's Diane Parry in what was the last tournament for Kvitova before retirement.

ESPN Research and The Associated Press contributed to this report.